Iron-based phosphate binders: do they offer advantages over currently available phosphate binders?
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منابع مشابه
Iron-based phosphate binders: do they offer advantages over currently available phosphate binders?
Increased cardiovascular morbidity and mortality has been associated with the hyperphosphatemia seen in patients with end-stage chronic kidney disease (CKD). Oral phosphate binders are prescribed in these patients to prevent intestinal absorption of dietary phosphate and reduce serum phosphate. In prospective observational cohorts they have shown to decrease all-cause and cardiovascular mortali...
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1. Simeone DM, Sandelin K, Thompson NW. Undescended superior parathyroid gland: a potential cause of failed cervical exploration for hyperparathyroidism. Surgery 1995; 118: 949–956 2. Manley NR, Selleri L, Brendolan A et al. Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs. Dev Biol 2004; 276: 301–312 3. Billingsley KG, Douglas LF, Doppman J...
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The use of an oral phosphate binder is a promising and most practical strategy for the prevention of vascular calcification in patients with chronic kidney disease (CKD). To secure the safety: 1) the oral phosphate binder must not cause adverse effects in the gastrointestinal tract; 2) the oral phosphate binder should be non-absorbable or barely absorbable through the gastrointestinal tract, or...
متن کاملEffects of phosphate binders in moderate CKD.
Some propose using phosphate binders in the CKD population given the association between higher levels of phosphorus and mortality, but their safety and efficacy in this population are not well understood. Here, we aimed to determine the effects of phosphate binders on parameters of mineral metabolism and vascular calcification among patients with moderate to advanced CKD. We randomly assigned ...
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To cite: Patel P, Antoniou S, Popat R. Eur J Hosp Pharm 2015;22: 18–22. ABSTRACT Objectives The aim of this study was to determine patient specific perceptual and practical barriers to adherence to phosphate binders. The second stage aimed to determine the effectiveness of an adherence enhancing strategy trialled by patients. Methods A prospective, cross sectional study of patients attending a ...
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ژورنال
عنوان ژورنال: Clinical Kidney Journal
سال: 2014
ISSN: 2048-8505,2048-8513
DOI: 10.1093/ckj/sfu139